ABSTRACT
Objective: To investigate the blood glucose management of diabetic patients during the fight against corona virus disease 2019 (COVID-19) in Wuhan, China. Method(s): A questionnaire survey was conducted on diabetic patients receiving hypoglycemic drugs in wuhan, hubei province from February 16, 2020 to February 20, 2020. The questionnaire included participants' basic information, the management of blood glucose, and the prevention and control of COVID-19. SPSS 19.0 was used for statistical analysis, and chi2 test was used for comparison between the two groups. Result(s): A total of 152 valid questionnaires were retrieved. 86 cases (56.6%) diabetic patients achieved glycemic control. 80 cases (52.6%) could regularly monitor their blood glucose. 48 cases (31.6%) had the difficulty in the management of blood glucose for purchasing medicines. They also had the difficulties in adjusting blood glucose in the outpatient of endocrinology departments (31 cases, 20.4%), adherence to appropriate exercise (28 cases, 18.4%) and eating the balanced diet (16 cases, 10.5%). When faced with medical problems, 73 cases (48.0%) seek help from hospital out-patient clinics. Nearby pharmacies (78 case, 51.3%) or hospital outpatient (63 cases, 41.5%) were the main ways to purchase medicines for diabetic patients. 133 cases (87.5%) took medicines regularly. 39 cases (25.7%) and 17 (11.2%) diabetic patients were affected by the COVID-19 epidemic and changed or discontinued the original treatments. There was statistically significant in the proportion of discontinuation of hypoglycemic drugs between different drug treatment regiments and subgroups with diabetes course (chi2=13.30, P<0.01;chi2=8.72, P<0.05). Only 16 cases (10.5%) showed that their community health service organizations had specially trained diabetic management team. Conclusion(s): This survey suggests that the diabetic patients in Wuhan had not paid enough attention to blood glucose monitoring, and their blood glucose control standards need to be further improved. In terms of the present problems, more comprehensive blood glucose management measures need to be developed to help diabetic patients fighting against COVID-19.Copyright © 2020 by the Chinese Medical Association.
ABSTRACT
Clinical data and follow-up of a case of congenital disorder of glycosylation type Ia (CDG-Ia) combined with dilated cardiomyopathy admitted to the Department of Cardiology, Children's Hospital of Nanjing Medical University were analyzed retrospectively.The 5-year-old female patient was admitted in December 2016 due to recu-rrent shortness of breath for 2 months.Clinical symptoms and signs included repeated attacks of shortness of breath, physical retardation, malnutrition, binocular esotropia, multiple episodes of hypoglycemia, hepatosplenomegaly, hypotonia and other multi-system damages.Cardiac echocardiography suggested the feature of dilated cardiomyopathy, including the significant enlargement of the left ventricle, and decreased systolic function.Genetic testing revealed a compound heterozygous mutation in the PMM2 gene, and as a result, the patient was diagnosed as CDG-Ia.The patient's condition improved after symptomatic treatments such as Cedilanid, Dopamine, Dobutamine, Furosemide, as well as support treatments like myocardium nutrition, blood sugar maintenance, liver protection, etc.After discharge, the patient was given oral Digoxin, Betaloc, Captopril and diuretics, and hypoglycemia-controlling agents.The patient was followed up every 3-6 months.After more than 2 years of follow-up, the heart function and heart enlargement gradually returned to normal.During the Corona Virus Disease 2019 outbreak, self-withdrawal continued for 2 months.Re-examinations showed decreased cardiac function and enlarged left ventricle again.Medications were resumed again, and the patient was followed up closely.This case report suggested that CDG-Ia may be associated with dilated cardiomyopathy, and the cardiac phenotype may be improved by symptomatic supportive treatment.Copyright © 2021 by the Chinese Medical Association.
ABSTRACT
Objective: To investigate the blood glucose management of diabetic patients during the fight against corona virus disease 2019 (COVID-19) in Wuhan, China. Method(s): A questionnaire survey was conducted on diabetic patients receiving hypoglycemic drugs in wuhan, hubei province from February 16, 2020 to February 20, 2020. The questionnaire included participants' basic information, the management of blood glucose, and the prevention and control of COVID-19. SPSS 19.0 was used for statistical analysis, and chi2 test was used for comparison between the two groups. Result(s): A total of 152 valid questionnaires were retrieved. 86 cases (56.6%) diabetic patients achieved glycemic control. 80 cases (52.6%) could regularly monitor their blood glucose. 48 cases (31.6%) had the difficulty in the management of blood glucose for purchasing medicines. They also had the difficulties in adjusting blood glucose in the outpatient of endocrinology departments (31 cases, 20.4%), adherence to appropriate exercise (28 cases, 18.4%) and eating the balanced diet (16 cases, 10.5%). When faced with medical problems, 73 cases (48.0%) seek help from hospital out-patient clinics. Nearby pharmacies (78 case, 51.3%) or hospital outpatient (63 cases, 41.5%) were the main ways to purchase medicines for diabetic patients. 133 cases (87.5%) took medicines regularly. 39 cases (25.7%) and 17 (11.2%) diabetic patients were affected by the COVID-19 epidemic and changed or discontinued the original treatments. There was statistically significant in the proportion of discontinuation of hypoglycemic drugs between different drug treatment regiments and subgroups with diabetes course (chi2=13.30, P<0.01;chi2=8.72, P<0.05). Only 16 cases (10.5%) showed that their community health service organizations had specially trained diabetic management team. Conclusion(s): This survey suggests that the diabetic patients in Wuhan had not paid enough attention to blood glucose monitoring, and their blood glucose control standards need to be further improved. In terms of the present problems, more comprehensive blood glucose management measures need to be developed to help diabetic patients fighting against COVID-19.Copyright © 2020 by the Chinese Medical Association.
ABSTRACT
The COVID-19 Pneumonia with diabetic ketoacidosis is a dreadful health condition. Diabetic ketoacidosis is one of the severe metabolic complications and it can be precipitated by infection. We presented a case of 48 years female with no known comorbidities who presented with COVID-19 symptoms and with Diabetic Ketoacidosis. The case presented with elevated inflammatory markers, high anion gap metabolic acidosis with type I respiratory failure. During admission, the oxygen saturation had marked drop, later her improvement was steady followed by gradual tapering of the oxygenation. Marked improvement was noticed in the subsequent follow-up. COVID-19 infection can be precipitated by preexisting diabetes or newly diagnosed diabetes and the severity of COVID-19 infection is more pronounced in patients with diabetes mellitus, thus should be managed timely and accordingly. The scarce studies among the COVID-19 cases with diabetic ketoacidosis reflect the need for further studies for the availability of a wider range of information. Copyright © 2021, Kathmandu University. All rights reserved.